Studies concerning transdermal CO2 therapy by Chief Science Officer Richard Rivers MD, PhD.
Dioxyfin transdermal carbon dioxide is ideal for osteoarthritis therapy. It decreases inflammation through the direct actions of NF-κB signaling3 and it reduces reactive oxygen species4. As a consequence of the application of carbon dioxide directly to the affected tissue and joints, inflammation is decreased and the destructive actions of the ROS neutralized. With that, pain and swelling is reduced and the result is a healthy environment for the formation of new tissue and collagen.
Read MoreThis paper presents some information about the pathology of acute and chronic laminitis. It then discusses some of the physiological effects of carbon dioxide and describes how elevated levels of carbon dioxide, achieved by diffusion through the skin, are predicted to have specific effects on inflammation, blood flow, and reactive oxygen species that will work together to alleviate laminitis.
Read MoreThis paper describes the biological mechanisms involved in angiogenesis and reveals multiple studies showing transdermal carbon dioxide can play a critical role in the formation of new blood vessels.
Read MoreThe paper discusses the use of transdermal carbon dioxide and lists the studies that document positive outcomes from this therapy for fractures, blood flow disorders related to peripheral vascular disease, skin flaps for plastic surgery, Raynaud’s Disease, cancer, and exercise recovery.
Read MoreThis paper describes some of the pathophysiology of wound healing. It then presents six published methods for treating the healing wound and defines what each method offers in the treatment of the wound and how it might fit in with a busy veterinarian practice.
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